Molecular Biology Resources
European Bioinformatics Institute (EBI)
The European Bioinformatics Institute (EBI) is a non-profit academic organisation that forms part of the European Molecular Biology Laboratory (EMBL). The EBI is a centre for research and services in bioinformatics. The Institute manages databases of biological data including nucleic acid, protein sequences and macromolecular structures. The section "Bioinformatics: Products and Services" features one of the largest collections of databases and tools for Molecular Biology on the internet. The database section contains: literature databases, microarray databases, nucleotide databases, protein databases and structure databases. The tools section facilitates homology searches, protein function analysis, sequence analysis, structural analysis and other useful operations.
National Center for Biotechnology Information (U.S.)
The National Center for Biotechnology Information creates public databases, conducts research in computational biology, develops software tools for analyzing genome data, and disseminates biomedical information. The site is divided into the following sections: BLAST (Basic Local Alignment Search Tool), OMIM (Online Mendelian Inheritance in Man), Taxonomy and Structure. The latter contains MMDB, a database of macromolecular 3D structures, as well as tools for their visualization and comparative analysis. MMDB, the Molecular Modeling Database, contains experimentally determined biopolymer structures obtained from the Protein Data Bank. The BLAST section offers a variety of BLAST engines for nucleotide- and protein sequences and facilitates BLAST searches of the human genome, various animals and pathogens. The site also offers good tutorials for novices.
The Wellcome Trust Sanger Institute is one of the leading genomics centres in the world, dedicated to analysing and understanding genomes. Formerly the Sanger Centre, the Wellcome Trust Sanger Institute was founded in 1993 by the Wellcome Trust and the UK Medical Research Council (MRC). The site features useful compilations and links to software packages, BLAST Search Services and Database Search Services. Another section - Genome Sequencing and Annotation - allows you to retrieve information about individual chromosomes (e.g. human, mouse, pathogen) and lists links to ongoing projects. The section "Genomics & Genetics at the Sanger Institute" provides information on microarrays, the Human Genome Project and the Cancer Genome Project, immunogenomics, proteomics, bioinformatics and a number of other aspects.
The Institute for Genomic Research (TIGR)
Founded in 1992, The Institute for Genomic Research (TIGR) is a not-for-profit research institute whose primary research interests are in structural, functional and comparative analysis of genomes and gene products from a wide variety of organisms including viruses, eubacteria, archaea and eukaryotes (plants, animals, fungi and protists such as the malarial parasite). The website features many useful tools and databases such as the Comprehensive Microbial Resource (CMR) - a tool that allows researchers to access all of the bacterial genome sequences completed to date. The TIGR Parasites Database contains links to the genome projects for T.brucei and T. cruzi, B. malayi, E. histolytica, Pl. falciparum and Pl. vixax; the TIGR Fungal Database contains information on the projects for Cryptococcus neoformans and Aspergillus fumigatus. Two further sections are dedicated to Functional Genomics and Software Resources - the latter provides links to free software for gene finding/annotations, alignment, sequencing/finishing, microarrays and grid computing. A great resource.
This site is run by the U.S. Department of Energy / Office of Science. It contains a large, detailed section with links and information about the Human Genome Project (news, research topics, publications, resources) as well as the Microbial Genome Programme. Another section features resources for educators and students, while another covers medical aspects of genetics (gene testing, diseases, gene therapy, pharmaceuticals, genetic counselling).
The ExPASy (Expert Protein Analysis System) proteomics server of the Swiss Institute of Bioinformatics (SIB) is dedicated to the analysis of protein sequences and structures as well as 2-D PAGE. The site features links to a variety of protein and enzyme databases as well as a large collection of tools and software packages related to proteomics, DNA to protein translation, BLAST and structure prediction amongst others.
UCLA Molecular Biology Tutorials
This website provides excellent tutorials on a range of topics related to Molecular Biology. The contents is divided into 2 broad topics - 1. Gene Expression and 2. Gene Cloning. The Gene Expression section contains tutorials on transcription, splicing and translation. The Gene Cloning section contains material about restriction enzymes, sequencing, Southern blotting and PCR. The tutorials are supported by great graphics and animations. Viewing will require Flash Player and QuickTime Player (available free of charge / click name to download).
The
Dictionary of Cell and Molecular Biology
This site features an online-version of the third edition of "The Dictionary of Cell & Molecular Biology" published by Academic Press. A simple search engine retrieves documents related to the search terms entered. The explanations - as can be expected from a dictionary - are rather concise, but crosslinking allows you to look up other terms that appear in the text. Contains everything you wanted to know about cell biology but were too afraid to ask. Great for beginners.
World Index of Molecular
Visualization Resources
A visitor maintained site with a huge collection of sites related to biochemical and molecular modelling and visualization. Topics covered include: organic chemistry, inorganic chemistry, crystal structures, DeepView resources, galleries of molecular images (e.g. Atlas of Macromolecules, DNA Image Gallery, images of viral enzymes/components, images of drugs etc.) and free software for molecular visualization and modelling. The navigation is straight forward - all sections can be searched according to title or subject. A great resource.
Restriction
Endonuclease Database - New England BioLabs
Excellent resource for information on restriction enzymes (despite the commercial character). Restriction enzymes can be searched alphabetically or by entering the desired recognition sequence into the enzyme finder search engine. The site also features the NEBcutter tool which will take a DNA sequence and find the large, non-overlapping open reading frames using the E.coli genetic code and the sites for all Type II restriction enzymes that cut the sequence just once. By default, only enzymes available from NEB are used, but other sets may be chosen.
Provides guidance on how to find antibodies (including a number of commercial links). Other sections feature online educational resources about antibodies as well as immunology and biotechnology resources. The "database/software" section contains further useful links related to antibodies, immunohistology, hybridomas and cell cultures. A great resource for anything related to antibodies.
John Kyrk's Cell Biology Animations
This site - run by John Kyrk - features amazing animations and graphics about cell biology including: DNA (structure, replication, transcription, translation), cell index (chromosome structure, membranes, mitochondria), meiosis and mitosis as well as a number of biochemical processes.
Molecular Biology Protocols from Highveld.com
This website offers a comprehensive collection of molecular biology protocols, molecular biology methods, molecular biology techniques, molecular biology procedures, molecular biology strategies, general laboratory protocols, laboratory techniques, laboratory methods and procedures. Most of the protocols come from the websites of other scientists - however, this can be a useful resource for lab work.
Centers for Disease Control and Prevention (CDC)
The Centres for Disease Control are part of the U.S. Department of Health and Human Services. The website offers a plethora of information on health-related topics including the following: birth defects, disabilities, diseases and conditions, emergency preparedness and response, environmental heath, genetics and genomics, health promotion, vaccines and immunisations. The site also provides links to the two main publications - the Morbidity and Mortality Weekly Report (MMWR) and the Emerging Infectious Diseases Journal (both full text without subscription / charge). Other links provide growth charts and national, epidemiological data.
National Institutes of Health (NIH)
The NIH is part of the U.S. Department of Health and Human Services. The "Health Topics" section of this site provides information on a variety of diseases, including recent research, treatment options and support groups and provides links to topic-related agencies (e.g. the National Institute of Allergy and Infectious Diseases). Another section outlines details of grants, funding and research training. The "Scientific Resources" section provides links to a number of resources within the NIH - such as the Mammalian Gene Collection, the Human Embryonic Stem Cell Registry and the AIDS Reagent Program.
World Health Organisation (WHO)
This website offers a multitude of useful information such as country-specific epidemiological data, disease outbreaks, data on immunisation and data on notifiable diseases. Another large section - called "Health Topics" - contains fact sheets about a large variety of diseases, health policies, press releases and information on current WHO programmes.
Molecular Biology Organisations and Associations
American Society for Biochemistry and Molecular
Biology (ASBMB)
Australian Society for Biochemistry and Molecular
Biology
British Society for Cell Biology
Canadian Society of Biochemistry and Molecular
& Cellular Biology
Croatian Society of Biochemistry
Czech Society for Biochemistry and Molecular
Biology
Danish Society for Biochemistry
and Molecular Biology
European Life Scientist Organisation (ELSO)
European Life Sciences Forum (ELSF)
European Molecular Biology Network (EMBnet)
European Molecular Biology Organization (EMBO)
Federation of African Societies of
Biochemistry and Molecular Biology (FASBMB)
Federation of American Societies for Experimental
Biology (FASEB)
Federation of Asian and
Oceanian Biochemists and Molecular Biologists (FAOBMB)
Federation of European Biochemical Societies (FEBS)
Gesellschaft für Biochemie und Molekularbiologie
e.V.
Hellenic Society of Biochemistry and Molecular
Biology
International Federation of Clinical Chemistry
and Laboratory Medicine (IFCC)
International Union of Biochemistry and
Molecular Biology (IUBMB)
Israel Society for Biochemistry
and Molecular Biology (ISBMB)
Österreischische Gesellschaft für
Biochemie und Molekuarbiologie
Magyar Biokemiai Egyesület / Hungarian
Biochemical Society
Nederlandse Vereniging voor Biochemie en
Moleculaire Biologie
Pan American Association for Biochemistry
and Molecular Biology (PABMB)
Polskie Towarzystwo Biochemiczne
/ Polish Biochemical Society
Romanian Society of Biochemistry and Molecular
Biology
Schweizerische Gesellschaft für Biochemie
Slovak Society for Biochemistry
and Molecular Biology
Sociedad Espanola de Biochimica y Biologia Molecular
(SEBBM)
Sociedade Portuguesa de Bioquimica
Societa Italiana di Biochimica e Biologia
Moleculare
Societas Biochemica, Biophysica
et Microbiologica Fenniae
Societe Belge de Biochimie et de Biologie
Moleculaire
Societe Francaise de Biochimie
et de Biologie Moleculaire (SFBBM)
Svenska Föreningen för Biokemi och Molekylärbiologi
(SFBM)
Molecular Biology Journals / Genetics Journals
American
Journal of Human Genetics -
abstracts
, full-text requires
subscription, pay-per-article
American
Journal of Medical Genetics -
abstracts, full-text requires
subscription, pay-per-article
Annals
of Human Genetics -
abstracts, full-text requires
subscription, pay-per-article
Annual
Review of Genetics - abstracts,
full-text requires subscription, pay-per-article
Annual
Review of Genomics and Human Genetics -
abstracts, full-text requires
subscription, pay-per-article
Applied Microbiology and Biotechnology -
abstracts, full-text requires
subscription, pay-per-article
BBA Gene Structure and Expression -
abstracts, full-text requires
subscription, pay-per-article
Biochemical Genetics
- abstracts, full-text requires
subscription, pay-per-article
Biomolecular
Engineering - abstracts,
full-text requires subscription, pay-per-article
Bioprocess and Biosystems Engineering
- abstracts, full-text requires
subscription, pay-per-article
Biotechnology
Advances - abstracts,
full-text requires subscription, pay-per-article
Biotech
Journal - free full
text access 
Biotechnology
and Applied Biochemistry -
abstracts, full-text requires
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Biotechnology and Bioengineering -
abstracts, full-text requires
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Biotechnology
Letters - abstracts,
full-text requires subscription, pay-per-article
Biotechnology
Progress - abstracts,
full-text requires subscription, pay-per-article
Cancer
Gene Therapy - abstracts,
full-text requires subscription, pay-per-article
Cancer
Genetics and Cytogenetics -
abstracts, full-text requires
subscription, pay-per-article
Chromosoma
- abstracts,
full-text requires subscription, pay-per-article
Chromosome
Research - abstracts,
full-text requires subscription, pay-per-article
Clinical
Genetics - abstracts,
full-text requires subscription, pay-per-article
Comparative
and Functional Genomics -
abstracts, full-text requires
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Critical Reviews in Biotechnology -
abstracts, full-text requires
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Current Genetics -
abstracts, full-text requires
subscription, pay-per-article
Current
Opinion in Genetics & Development -
abstracts, full-text requires
subscription, pay-per-article
Electronic
Journal of Biotechnology -
free full text access
EMBO Journal
- abstracts, full-text requires
subscription, pay-per-article
European Journal of Human Genetics -
abstracts, full-text requires
subscription, pay-per-article
European
Journal of Immunogenetics -
abstracts, full-text requires
subscription, pay-per-article
Expert
Reviews in Molecular Medicine -
abstracts, full-text req.
subscr., pay-per-article
the site also features a collection of animations
Fungal
Genetics and Biology -
abstracts, full-text requires
subscription, pay-per-article
Gene
- abstracts,
full-text requires subscription, pay-per-article
Gene
Function & Disease -
abstracts, full-text requires
subscription, pay-per-article
Gene Therapy - abstracts,
full-text requires subscription, pay-per-article
Genes and Immunity -
abstracts, full-text requires
subscription, pay-per-article
Genetic Engineering News - abstracts,
free subsciption available
Genetical Research -
abstracts, full-text requires
subscription, pay-per-article
Genetics
- abstracts,
full-text requires subscription, pay-per-article
Genetics in Medicine -
abstracts, full-text requires
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Genome
Biology - some articles free
full text access , some
of the contents requires subscription
Human Genetics -
abstracts, full-text requires
subscription, pay-per-article
Human Genome News -
free full text access
Human Molecular Genetics -
abstracts, full-text requires
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Infection,
Genetics and Evolution -
abstracts, full-text requires
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Journal
of Biotechnology -
abstracts, full-text requires
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Journal
of Gene Medicine -
abstracts, full-text requires
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Journal of Human Genetics -
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Journal of Molecular Evolution -
abstracts, full-text requires
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Journal of Molecular Medicine -
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Mammalian Genome -
abstracts, full-text requires
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Molecular Genetics and Genome -
abstracts, full-text requires
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Molecular
and Cellular Probes -
abstracts, full-text requires
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Molecular Biotechnology -
abstracts, full-text requires
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Nature Biotechnology -
abstracts, full-text requires
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Nature
Genetics - abstracts,
full-text requires subscription, pay-per-article
Nucleic Acids Research -
abstracts, full-text requires
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Nucleosides,
Nucleotides and Nucleic Acids -
abstracts, full-text requires
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Pharmacogenetics -
abstracts, full-text requires
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Pharmacogenomics
- abstracts,
full-text requires subscription, pay-per-article
Pharmacogenomics Journal (Nature) -
abstracts, full-text requires
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Pharma
Genomics - free full
text access
Protein Engineering, Design and Selection -
abstracts, full-text requires
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Protein
Expression and Purification -
abstracts, full-text requires
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Protein
Science - abstracts,
full-text requires subscription, pay-per-article
Proteins:
Structure, Function and Bioinformatics -
abstracts, full-text requires
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RNA - abstracts,
full-text requires subscription, pay-per-article
Somatic
Cell and Molecular Genetics -
abstracts, full-text requires
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TAG Theoretical and Applied Genetics
- abstracts,
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Transgenic
Research -
abstracts, full-text requires
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Trends
in Biotechnology -
abstracts, full-text requires
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Trends
in Genetics -
abstracts, full-text requires
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Virus
Genes -
abstracts, full-text requires
subscription, pay-per-article
World
Journal of Microbiology and Biotechnology
- abstracts,
full-text requires subscription, pay-per-article
Other useful links
PubMed probably requires little explanation - it is the most widely used search-engine/database in Medicine. PubMed is provided by the U.S. National Library and contains 12 million citations from 4600 biomedical journals worldwide. Articles can be searched for according to author, keyword or subject, while MeSH allows the use of categories (indexing system) to find relevant articles.
The Cochrane Collaboration is an international, non-profit organisation providing up-to-date information about the effects of health care. The site contains a large database of evidence based, systematic reviews about treatments and interventions. However, the Cochrane Library itself can only accessed with password.
The National Guideline Clearinghouse (NGC)
This website is a comprehensive database of evidence-based clinical practice guidelines and related topics produced by the Agency for Healthcare Research and Quality (part of the U.S. Department of Health and Human Services) in partnership with the American Medical Association (AMA). Key features include: structured abstracts of guidelines, access to full text guidelines/articles and Palm-based PDA downloads. A search engine facilitates the retrieval of the relevant documents. The site contains a large number of investigation- and management-guidelines related to Paediatric Infectious Diseases, Immunology and vaccination.
The Karolinska Institute University Library
The library homepage of the Karolinska Institute in Stockholm contains an enormous up to date database with a large number of links to websites related to bacterial infections, mycoses, viral diseases, parasitic diseases and Immunology. Another section contains links related to congenital, hereditary and neonatal diseases. Sections can either be browsed according to topic - alternatively, a search engine facilitates the search according to keywords.
Public Health Image Library by CDC (PHIL)
The PHIL provided by the CDC contains a large number of photos, illustrations and a few audio-visual files. The site contains historical images as well as clinical photos related to paediatric infectious diseases, paediatric immunology, tropical medicine and other specialties. Other images include: histology, cultures, posters (e.g. vaccination campaigns), electron micrographs, images of vectors, x-rays and illustrations. The images are in the public domain and can be accessed and used free of charge.
Interactive Human Atlas by Health Scout
This website features 3D computer animated video sequences, still images and models of pathogens. Although the contents is geared more towards lay persons the contents is entertaining and could be used for teaching purposes. Current topics include: allergies, immunisation, infectious diseases (AIDS, anthrax, herpes, hepatitis, influenza, lyme disease, meningitis, UTI) and numerous paediatric topics (e.g. Down's syndrome, ADHD).
Gray's Anatomy of the Human Body
This website features a complete online version of the classic 1918 publication by Henry Gray which includes 1,247 engravings. A search engine facilitates convenient navigation. The access is free of charge.
This website offers a wide range of articles (text-book style) on subjects related to Paediatrics, Infectious Diseases, Immunology and even Tropical Medicine. Most parts can be viewed without subscription/fees, but some features are only accessible to registered (and paying) users. The site also contains recent journal updates, medical image library and online CME. Other useful features are: medical dictionary (Stedman's), Medical Institution Finder (searches for medical schools, societies and organisations, libraries and medical centers) and links to a variety of medical journals.
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